Targeted juglone blocks the invasion and metastasis of HPV-positive cervical cancer cells
نویسندگان
چکیده
منابع مشابه
ISOLATED METASTASIS OF CERVICAL CANCER TO THE ABDOMINAL WALL
ABSTRACT Carcinoma of the cervix is a common neoplasm and accounts for a considerable number of cervical diseases that lead to death in developing countries. In these countries early detection and improved methods of treatment have resulted in comparatively better control of the cancer and long survival however, invasive and metastatic disease still occurs. The authors present the case report ...
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S100A7 is an EF-hand calcium-binding protein that has been suggested to be implicated in cell proliferation, migration, invasion and tumor metastasis. However, its role in cervical cancer has not yet been fully clarified. The present study used immunohistochemistry analysis of S100A7 in clinical specimens of cervical cancer to show that S100A7 expression was significantly upregulated in cervica...
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Human wings apart-like (hWAPL) is reported to have an association with cervical cancer. In the present study, the role of hWAPL in cervical cancer stem cells (CCSCs) was evaluated. Cervical tumorspheres were generated from cervical cancer tissues cultured in stem cell medium, and the expression of hWAPL by the tumorspheres was detected using immunohistochemistry. hWAPL expression levels in the ...
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The rate of cervical cancer in Asians is deferent, based on the risk factors affecting and the rate of papiloma virus infection among females. Cervical cancer is one of the important cancers between Iranian women. In the present study the rate of cervical neoplasia was detected in Isfahan and some risk factors affecting the incidence of cervical cancer was analyzed. The human papiloma virus inf...
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Our previous study demonstrated a decreased expression of tumor susceptibility gene 101 (TSG101) in cervical cancer cells. To identify the mechanism responsible for TSG101 downregulation during cervical cancer development, we analyzed the TSG101 promoter using cis-element cluster finder software. One of the transcription factors whose binding site was detected in the TSG101 promoter was late SV...
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ژورنال
عنوان ژورنال: Journal of Pharmacological Sciences
سال: 2019
ISSN: 1347-8613
DOI: 10.1016/j.jphs.2019.06.013